Project: Efficacy and cost-effectiveness of new anticoagulants in patients with atrial fibrillation

Short description and summary (English)

Atrial fibrillation is a rhythm disturbance in the heart. Due to irregular electrical impulses, the atria and ventricles do not contract simultaneously as they normally do. This results in uneven blood flow and increased risk of blood clot formation. These clots may follow the blood flow and cause stroke or systemic embolism in other parts of the body. To prevent thromboembolic events, it is recommended that patients with atrial fibrillation and intermediate to high risk of stroke receive blood-thinning treatment. In this project we will investigate the efficacy and cost-effectiveness of new anticoagulants compared to warfarin for stroke prevention in patients with atrial fibrillation.